During the rule of Alauddin Husain Shah, Muazzamabad (currently, Muazzampur) was the administrative headquarters of East Bengal.

On 21 April, the Pakistan army killed 18 people and burned a few hundred houses in the Rajgati, Shuvokhila, and Kaliganj areas.

On 17 November, a total of 27 freedom fighters including Illias Uddin Bhuiyan, Shamsul Haque, Zillul Baki, Thana Awami, and Shahnewaz Bhuiyan were killed in a battle with Pakistan.

According to the 2011 Census of Bangladesh, Nandail Upazila had 87,523 households and a population of 402,727.

Nandail has a literacy rate (age 7 and over) of 40.38%, compared to the national average of 51.8%, and a sex ratio of 1032 females per 1000 males.

Jute, paddy, wheat, potato, gourd, and aubergine are the main crops.

There are few flour and textile mills, and other industries include cottage industries, weaving, bamboo work, blacksmiths, goldsmiths, potteries, tailoring, welding, and wood work.