Nathan Updegraff (September 3, 1750 in York County, Pennsylvania - March 3, 1827 in Mount Pleasant, Jefferson County, Ohio) was an American Quaker minister, abolitionist and founder and delegate to Ohio's first constitutional convention in 1802.

[1] He descended from a long line of ministers and elders of the Quaker church,[2] which belong to the Op den Graeffs, a German family of Dutch origin.

[3] He was a direct descendant of Herman op den Graeff, Mennonite leader of Krefeld, and his grandson Abraham op den Graeff, one of the founders of Germantown, and who in 1688 was a signer of the first protest against slavery in colonial America.

[10] Updegraff built the first Mill in Mount Pleasant Township, manufactured paper and owned estates of 1,586 acres.

[7] Nathan Updegraff and Anne Love (around 1757-1787/88) had following children:[11] Children of Nathan Updegraff and Ann Lupton (9 June 1767 - 25 December 1833):[11] There is a reference about the Op den Graeff glass paintings of Krefeld with a description of Herman op den Graeffs coat of arms was found in the estate of W. Niepoth (op den Graeff folder) in the archives of the city of Krefeld, who noted a letter dated November 17, 1935 from Richard Wolfferts to Dr Risler: Saw the Coat of Arms glass pane in the old museum: 'Herman op den Graeff und Grietgen syn housfrau' or the like.