Natshin Medaw (Burmese: နတ်ရှင် မယ်တော်, or နတ်သျှင် မယ်တော်, pronounced [naʔʃɪ̀ɴ mɛ̀dɔ̀]) was crown princess of Toungoo Dynasty of Burma (Myanmar) from 1581 to 1586.
She later moved to Pegu (Bago) when she was married to Mingyi Swa, her maternal first cousin, and her paternal half-cousin, once removed.
It contributed to the fallout between her powerful parents and the high king Nanda that ultimately resulted in Ava's revolt in 1583–1584.
In the letter, she complained that her husband spent much of the time pursuing Princess Yaza Datu Kalaya, and that when she confronted him about the matter, he pushed her to the bedpost.
Back from Siam, the king was extremely unhappy to learn the news, and put Natshin Medaw in the same house as her mother with attendants.