The Navy Region Southwest is one of eleven current naval regions responsible to Commander, Navy Installations Command for the operation and management of Naval shore installations in California, Nevada, Utah, Arizona, Colorado, New Mexico.

Navy Region Southwest comprises the former areas of the Eleventh and Twelfth Naval Districts.

Naval bases and stations throughout the region were expanded to provide maximum support to combatant forces of the fleet.

With Korea, Vietnam and "cold war" commitments, fleet support activities under Commander Naval Base San Diego remained at a very high level.

When the Twelfth Naval District was disestablished in 1977, Navy Southwest assumed all its duties and responsibilities, and annexed the areas of Colorado, Utah, the rest of Nevada, and the rest of California The Eleventh Naval District was disestablished on 30 September 1980.