Nelson Gregory Spruce (born December 5, 1992) is a former American football wide receiver.

[5] As a senior in 2015, Spruce finished his college career by breaking the all-time Pac-12 receptions record in a game versus UCLA.

[7] After going undrafted in the 2016 NFL draft, Spruce signed as an undrafted free agent with the Los Angeles Rams[9] The rookie made a big impression in his first preseason game, catching six passes for 51 yards and a touchdown to help the Rams defeat the Dallas Cowboys 28–24 in the team's first game back in Los Angeles after relocating from St.

[11] Spruce stayed with the Rams through the offseason program, and caught six passes against Dallas in the preseason opener, but he saw little action in the following weeks as he had to compete for a roster spot with newly arrived receivers Robert Woods, Sammy Watkins, Cooper Kupp, and Josh Reynolds.

[19] During the third week of the AAF season against the San Antonio Commanders, Spruce caught four passes for 50 yards and two touchdowns in a 31–11 victory.

[22] By the time the 2020 XFL season was suspended due to the COVID-19 pandemic, Spruce had only played in the first three out of a possible five games, but had caught 20 passes for 256 yards and 2 scores,[23] and was named to both the XFL mid-season awards list,[24] and was one of the highest rated receivers according to Pro Football Focus.