4 species (see text) Neopilina is a highly derived genus of modern monoplacophoran.

[5] The post-oral tentacles are equated with bivalves' labial flaps, cephalopods' arms, and scaphopods' captacula.

[5] Cuticular hardenings around the mouth of the organism are considered to be jaw-like and not far removed from the beaks of cephalopods or the jaws of many gastropods.

[8] In 2017, a deep-sea expedition by the Okeanos Explorer off the coast of American Samoa filmed the first-ever high-resolution video of a monoplacophoran in its natural habitat.

The individuals may belong to an undescribed species, with five pairs of long gills clearly visible.