The novelty of the building was also reflected by its then decidedly modern style, probably the work of architects and artists from Switzerland.

The pilasters of the three floors are crowned (from top to bottom) with Tuscan, Ionian and Corinthian capitals.

Strasbourg's other Renaissance civic buildings and palaces, such as the butcher's hall Grosse Metzig (now housing the Musée historique) or the Hôtel de Boecklinsau[4] were all built or started in the decade following the opening of the Neubau.

It became the Chamber of commerce in 1792 and was refurnished by orders of Napoleon in 1802; thus the reception rooms now display Baroque tapestries and early 19th-century furniture.

In 1867, the architect, Eugène Petiti (1809–1883) added an aisle on the south side of the building, exactly replicating the 1580s style.