Neuron doctrine

The neuron doctrine is the concept that the nervous system is made up of discrete individual cells, a discovery due to decisive neuro-anatomical work of Santiago Ramón y Cajal and later presented by, among others, H.

He appropriated the concept not from his own research but from the disparate observation of the histological work of Albert von Kölliker, Camillo Golgi, Franz Nissl, Santiago Ramón y Cajal, Auguste Forel and others.

[4] Schwann was expanding on the proposal of his good friend Matthias Jakob Schleiden the previous year that all plant tissues were composed of cells.

In the first issue of the Revista Trimestral de Histología Normal y Patológica (May, 1888) Ramón y Cajal reported that the nerve cells were not continuous in the brain of birds.

Ramón y Cajal's discovery was the decisive evidence for the discontinuity of nervous system and the presence of large number of individual nerve cells.

[10] Furthermore, the phenomenon of cotransmission, in which more than one neurotransmitter is released from a single presynaptic terminal (contrary to Dale's law), contributes to the complexity of information transmission within the nervous system.