Two years later, it became the Ohio Asylum for the Education of Idiotic and Imbecile Youth (known today as the Columbus Developmental Center), which moved out to its current campus in 1868.

The Neville Mansion is a converted residential building on Main Street near Parsons Avenue in the Olde Towne East neighborhood of Columbus, Ohio.

[2] In 1868, the developmental center had acquired its own campus, and the mansion was sold that April to the Hannah Neil Mission and Home of the Friendless for $12,000.

Hannah Neil's orphanage was founded in April 1858 as the Industrial School Association, as it served to teach poor children the skills needed to build a better life.

The Neville Mansion acted as the organization's orphanage for temporarily neglected or dependent children for over a century, and replaced a homeless shelter established in 1865.

The mansion was extensively remodeled, and reopened in 1883 to serve women of all ages, boys up to 15, girls in need of rest or training for domestic service, "crippled children, transients", and others.

[5][6] A historical marker was placed at the site in 1983, identifying the house's role in helping children and families as the Neil Mission for 109 years.