Route 70 cuts across the middle of the state as a two-lane highway through the Pine Barrens in Burlington and Ocean counties.

The eastern section in Monmouth and Ocean counties is also a multilane divided highway that runs through suburban areas.

[1] From this interchange, it heads to the southeast on Marlton Pike, a six-lane divided highway that runs through suburban residential and commercial areas.

[1] The road enters Cherry Hill and comes to a cloverleaf interchange with Cuthbert Boulevard (CR 636) before crossing under NJ Transit's Atlantic City Line, a short distance to the south of the Cherry Hill Station.

In this area, Route 70 passes to the south of a retail and residential development at the former site of the Garden State Park Racetrack before crossing the intersection of Grove Street/Haddonfield Road (CR 644).

Past this intersection, the route narrows to four lanes and turns more to the east as it comes to the Ellisburg area.

[1][5] A short distance past I-295, Route 70 passes over the New Jersey Turnpike without an interchange before widening into an eight-lane highway and continuing east to the intersections of Greentree Road (CR 674) and Springdale Road (CR 673).

[5] It continues into a mix of suburban development and rural woods and farms as it crosses into Medford, coming to a crossroads with Medford-Evesboro Road (CR 618).

[1][5] After the intersection of North Main Street/Medford-Mount Holly Road (CR 541), the route leaves the suburban development and runs through a mix of woodland and farmland with occasional homes.

[1][5] Past here, Route 70 loses the Marlton Pike name and continues east into the heavily wooded Pine Barrens.

[1][5] It passes to the south of the Leisuretowne retirement village before entering predominantly rural areas, with two fire lanes paralleling the road on either side.

[5] Route 70 eventually turns slightly to the northeast and forms the border between Southampton to the north and Woodland Township to the south.

[1] The road passes to the south of the wooded Presidential Lakes Estates residential development before turning northeast through more of the Pine Barrens entirely within Pemberton Township.

[1] A short distance later, the two routes enter Manchester in Ocean County and continue east through a tract of the Brendan T. Byrne State Forest within the Pine Barrens as well as a corner of the Fort Dix Military Reservation.

Past Ridgeway Road (CR 571), the route heads through wooded suburban residential and business areas, crossing into Toms River.

[22] In July 2004, floods caused by heavy rain washed away a bridge along the route in Southampton Township, leading for it to be replaced.