New Oxford High School serves students from a portion of eastern Adams County.

In 2016, enrollment at New Oxford High School was reported as 1,208 pupils in 9th through 12th grades, with 34% of pupils eligible for a free lunch due to the family meeting the federal poverty level.

[4] Per the Pennsylvania Department of Education, 4% of the teachers were rated "Non-Highly Qualified" under the federal No Child Left Behind Act.

According to the National Center for Education Statistics, in 2010, New Oxford High School reported an enrollment of 1,281 pupils in grades 9th through 12th.

New Oxford High School offers a wide variety of clubs, activities and an extensive sports program.