[2] The main span is 1,270 feet (390 m), with a 135-foot (41 m) clearance over water to allow marine access to Port Newark.

It runs parallel to the earlier built Lehigh Valley Terminal Railway's Upper Bay Bridge.

It carries traffic on a toll regulated section of Interstate 78 along the New Jersey Turnpike to interchanges 14 through 14A.

Hoboken is just north of the entrance to Holland Tunnel which continues to Lower Manhattan in New York City.

From March 2014 until May 2019, during certain hours, the eastbound shoulder of the Turnpike Extension (including the bridge) was opened for normal traffic (by green arrows above, instead of red Xs), for a total of 5 lanes (3 eastbound, 2 westbound).