It is headquartered at the TV5 Media Center in Mandaluyong, Metro Manila, Philippines.

News5 generates news, infotainment, and entertainment output for TV5's media assets including its namesake network, RPTV, and other television stations, radio through the 105.9 True FM network, cable television through One News and One PH, internationally through Kapatid Channel, AksyonTV International, and news websites news5.com.ph and InterAksyon (part of the PhilStar Group).

Luchi Cruz-Valdes served as News5 and Public Affairs department chief since 2009 until her retirement on September 30, 2024.

These include the use of Live-Pack and a virtual news set, the first news FM station (105.9 True FM) and, prior to December 2013, the first and only 24-hour Filipino language free TV news channel (AksyonTV) along with the first English-language business news channel (Bloomberg TV Philippines) since October 5, 2015, prior to its launching in full broadcast, which is owned by Bloomberg L.P. in partnership with Bloomberg Television and Cignal.

It is also the first news organization to shoot and produce its newscasts in high-definition (HD) in April 2015 and the first digital (online)-only news video channel thru News5 Digital (formerly News5 Everywhere), which was launched on June 28, 2017.