He joined the Chinese Communist Party (CCP) in July 1983, on the verge of graduation.

He was appointed party branch secretary of Anhui Provincial Department of Construction (later reshuffled as Anhui Provincial Department of Housing and Urban-Rural Development) in December 2002, concurrently serving as director since January 2006.

[1][2][3][4] In March 2024, as China's property crisis worsened with China Vanke came under pressure to repay its private debts, Ni, in a press briefing, reiterated a stance that homes are "for living in, not for speculation.

"[5] In October 2024, China declared its property sector to have "bottomed out" and pledged a funding boost of 4 trillion yuan (562.18 billion USD).

During a ministry press conference, Ni emphasized positive signs of recovery noting encouraging home purchase data.