The Nichols House Museum is a museum at 55 Mount Vernon Street on Beacon Hill in Boston, Massachusetts.

[1] The house in which it is located was designed by the architect Charles Bulfinch, and built by Jonathan Mason, the politician, in 1804.

The museum is named for Rose Standish Nichols (1872–1960), the renowned landscape gardener, suffragist, pacifist, and member of the Cornish Art Colony, who lived in the house between 1885 and 1960.

The museum preserves the lifestyle of the American upper class during Nichols' lifetime, with turn-of-the-century period rooms.

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