Collaborators included David Adler, Mac Griswold, Howard Van Doren Shaw, and others.

Around 1921 Nichols served the American Society of Landscape Architects as Chairman of the Committee on the Garden Club of America.

[6] Nichols’ first commissioned project was her family’s garden at 'the Mastlands' in 1895, their summer home in Cornish, New Hampshire.

Rose added a piazza and laid out a formal garden enclosed with low stone walls.

The focal point of the garden was an apple tree that spread over a low pool and curving benches.

[12] In 1937, Nichols attended an event organized by the New York Society of the Descendants of Signers of the Independence Declaration.

[14] Rose Standish Nichols worked on parks and gardens for approximately 70 clients, in the United States and abroad: