It was centered around Niiya jin'ya in what is now part of the city of Ōzu, Ehime, and was ruled throughout its history by a cadet branch of tozama daimyō Katō clan.

Sadayasu died suddenly in 1623 without formally having appointed a successor, which would normally be cause for attainder; however, his eldest son Katō Yasuaki managed to secure an audience with Shogun Tokugawa Hidetada and was accepted as heir.

This move was made without the prior knowledge of Katō Yasuaki and was thus vehemently opposed by Ōzu Domain, and relations between the two branches of the clan was hostile for the next two centuries.

During the Boshin War, the domain fielded a company of commoner riflemen in the pro-imperial army, but otherwise played no role.

[4] A building of former jin'ya of the domain survives, and is designated a Ehime Prefectural Tangible Cultural Property.