Nijenhuis is a castle and an estate near Diepenheim in the municipality Hof van Twente, Netherlands (province Overijssel).
Johan van Beckum remarried, but transferred the Nijenhuis to his sister Adriana and her husband Gerrit Swaefken.
Philips Vingboons designed the central part of Nijenhuis, a Dutch neoclassicistic mansion built around 1662.
Abraham Martinus Sorg, town architect of Kampen, Overijssel modernised the building from 1791 to 1794.
The manor has remained largely intact with sheds, a workshop, a vegetable garden with orangery, a park with a tea house and an ice cellar.