He worked at various times as an apothecary, a commercial secretary and a hatter (from which he took the name Skoufas).
Skoufas left as a merchant for the Russian Empire for business purposes.
The three men came up with the idea of founding a secret organisation to prepare the ground for Greek independence.
For this purpose he went to Moscow but his ideas did not meet with the approval of many people of the local Greek community.
In 1818, the three partners moved to Constantinople to further their cause, but in July of that same year Skoufas fell ill and died.