He then completed his Master of Science degree majoring in Chemistry from the same university with the highest honors in the whole graduate program.

[7] Parajuli received his doctorate in biochemistry from the Department of Chemistry, Institute of Biomolecule Reconstruction at Sun Moon University, Korea in 2004.

From early 2010 to late 2011 he was a postdoctoral research associate at the Department of Chemistry at North Carolina State University, Raleigh, USA.

As of 2020, Parajuli has projects in the fields of computational chemistry, identification of enzyme inhibitors from plant sources to treat diabetes, and genetic characterization of actinomycetes for antibiotics production.

[13] He also is the chief scientific advisor to a project on investigation of secondary metabolites from natural products with a computational chemistry and immunochemistry approach on COVID-19.

He was employed as a South Korean government-sponsored invited scientist (Research Professor) at Sun Moon University, Korea between 2023 to 2024.