[2] The episode revolves around Dr. Gregory House (Hugh Laurie) noticing a man named Jeff (Paul Rae) in the emergency room, whom he thinks is "too nice".
Meanwhile, Dr. Eric Foreman (Omar Epps), thinks the other diagnostic team members don't respect him, while Amber Volakis (Anne Dudek) and House try to create a deal in which they can both spend time with Dr. James Wilson (Robert Sean Leonard).
House manipulates the team, Cameron (Jennifer Morrison), and Chase (Jesse Spencer), by swapping his own blood sample, leading them to believe he too has syphilis, perhaps the cause for his misanthropic personality and unfriendliness.
As punishment for not doing his team's reviews properly, and for breaking the rules she set between him and Amber, Cuddy has the two of them cleaning up bedridden patients together while outside in the corridor, Wilson smiles to himself, amused at the scene.
[8] In an interview with the Chicago Tribune, House creator David Shore commented that, although the characters of Cameron and Chase are not on screen as much as they used to be, they take on a different, and greater, weight with the "stuff" they are doing.
[10] In the episode Jason Lewis made a small uncredited appearance as Dr. Brock Sterling, a fictional doctor in House's favorite soap opera Prescription Passion.
[11] Jay Black of TV Squad noted that the first image in the episode after the two-and-a-half month writer's strike-induced break was a picket line.
[12] James Chamberlin of IGN stated that the scenes in which Amber and House were working out terms for sharing Wilson were "hysterical",[13] and graded the episode with an 8.5 (out of 10).
[13] Gina Dinunno of TV Guide thought the episode was pretty good, and the only thing she was not very fond of was that she felt that the characters of Robert Chase and Allison Cameron seemed "forced into the script".