Based on the earliest still existing copy, it is believed to have first been published on August 9, 1751, styled as the NOth Carolina Gazette.

[1][2] Previously, the lack of a paper for the colony meant residents had to rely on the Virginia Gazette (founded 1736) for news and advertising.

It was intended to be a weekly but its publication is believed to have been less regular, with occasional gaps in publishing, until the venture folded around 1759, or perhaps until 1761.

A letter to colonial governor William Tryon about the storm reported the damage: "Mr. Davis’s House [is] a mere Wreck, his printing Office broke to Pieces, his Papers destroyed and Types buried in the Sands."

Davis once again revived the Gazette on August 28, 1783, in conjunction with his son Thomas, and Robert Keith of Pennsylvania.