ND 14's southern terminus is at Interstate 94 (I-94) and U.S. Route 83 (US 83) west of Hague, and the northern terminus is a continuation as Manitoba Highway 21 (PTH 21) at the Canada–United States border.

[1] ND 14 begins at I-94 and US 83 near Sterling, and continues north for 73.2 miles until joining US 52 to go northwest just outside of Anamoose.

Along the 73.2 miles, ND 14 intersects with ND 36 outside of Wing, and ND 200 in rural Sheridan County near Denhoff.

After a brief concurrency with US 2, ND 14 leaves the highway in Towner and heads northwest to ND 5 for almost 40 miles.

After leaving the concurrency with ND 5 near Bottineau, ND 14 heads north to the Canadian Border for 12.8 miles, with the road into Canada continuing as Provincial Trunk Highway 21 towards Deloraine, Manitoba.