A plan to rebuild the hospital was announced by Boris Johnson in the 2019 General Election campaign, and in November 2020 a £54 million funding bid for improvement works was made by the Trust, Manchester City Council, and Manchester Health and Care Commissioning.

In 1927 a new dispensary and a separate block for operating theatres, X-ray, dental and recovery rooms was built.

The hospital had a bacteriological and pathological laboratory and was a registered training school for nurses both in general medical and surgical work and in midwifery.

In 1952 the hospital was recognised by Manchester University for clinical teaching and some of the senior medical staff were appointed honorary lecturers.

[7]Springfield Hospital had its origins in the new Manchester Union Workhouse, designed by Mills and Murgatroyd, and completed in 1853.

[16] To address health inequalities in Greater Manchester, the "healthier together" plan was published which included the unprecedented plan to demerge NMGH from Pennine Acute Hospitals NHS Trust and merge it into a newly formed NHS trust covering the City of Manchester & the Borough of Trafford by 2020.

[16] In march 2016, PAHT was rated as "inadequate" by the CQC, and the organisation asked the Salford Royal NHS Foundation Trust to assume immediate leadership of the trust prior to the future demerger of the North Manchester General Hospital site.