GDC dubbed the city, "North Port Charlotte", and it was incorporated under that name through a special act of the Florida Legislature on June 18, 1959.

Archaeological digs at the Little Salt Spring show that what is now North Port was inhabited by pre-Columbian Native Americans.

Evidence of their existence includes projectile points, a carved oak mortar, and a piece of a nonreturnable wooden boomerang.

[9] In 1954, the Mackle Brothers started the General Development Corporation with the intention of selling property in Florida to northerners.

Not only would they plat and sell a majority of what is now North Port, the company's employees served on the city's first council.

[11][12] On September 28, 2022, Hurricane Ian made direct landfall in Florida just south of Sarasota County.

North Port, in particular, experienced excessive flooding and the Holiday Park mobile home community was almost completely destroyed.

As of 2024, the current commission includes:[26] The city of North Port has its own police force, fire department, and waste management.