The Zone is subdivided into the six woredas (districts), which are Asgede, Tsimbla, La'ilay Adiyabo, Medebay Zana, Tahtay Adiyabo, Tahtay Koraro and Tselemti.

Major towns and cities in the zone include Shire, Sheraro, Inda Aba Guna, Selekleka, Adi Daero, May Tsebri.

[citation needed] Based on the 2007 Census conducted by the Central Statistical Agency of Ethiopia (CSA), this Zone has a total population of 736,805, of whom 368,254 are men and 368,551 women; 107,999 or 14.66% are urban inhabitants.

Two largest ethnic groups reported in Semien Mi'irabawi were the Tigray (96.81%), and Amhara (1.58%); all other ethnic groups made up 1.61% of the population.

This article about a location in the Tigray Region of Ethiopia is a stub.