Part of the Semien Mi'irabawi Zone, Tsimbla is bordered along the south by the Tekeze River which separates the woreda on the south from Tselemti and to the west by the Asgede, then on the northwest by Tahtay Adyabo, on the north by La'ilay Adiyabo, on the northeast by Tahtay Koraro, and on the east by Medebay Zana.

[1] Located in this woreda is Dedebit, where the Tigrayan People's Liberation Front established their first military base in February 1975.

The largest ethnic group reported in Asigede Tsimbela was the Tigrayan (99.21), and Tigrinya was spoken as a first language by 99.57%.

[4] A sample enumeration performed by the CSA in 2001 interviewed 21,495 farmers in this woreda, who held an average of 1.27 hectares of land.

For the land under cultivation in this woreda, 80.34% was planted in cereals, 2.17% in pulses, 5.85% in oilseeds, 0.41% in vegetables, and none in root crops.