The song was released as a single in 1988 on Enigma Records and reached #6 on the Billboard Hot 100 and #19 on the Mainstream rock charts.

[7][8] Music critic Steve Huey of Allmusic has also stated that "Nothin' But a Good Time" became one of the bands "most widely recognized signature songs" as well as that parent album Open Up and Say... Ahh!

[1] "Nothin' But a Good Time" was performed by Poison, with the cast of Rock of Ages, at the 63rd Tony Awards on June 7, 2009.

After the performance, as the band made their way backstage, a piece of the stage scenery collapsed on Bret Michaels.

It also appears in a 2022 Direct Line television advert featuring Tessa Thompson in character as Valkyrie (Marvel Comics).