The experimental film featured actors R. Madhavan, Neha Pendse, Kaveri, Nassar and Sreenivasan.

Roby Thomas migrates to the U.S. with the help of a priest and works as a barman in a casino in Las Vegas.

The film focuses on the inner turmoil of a youngster who seems to have a positive attitude towards life and emphasizes the importance of inter-personal relationship and friendship.

[3] The film was shot within 40 days in Las Vegas, Albuquerque and New Mexico in the United States, whilst scenes were later recorded in New York City.

[7] Whilst one reviewer cited that "given the present crisis in Malayalam films where good themes are in short supply, "Made in USA" is certainly a welcome change";[8] another cited that the movie "left audience confused", describing the film as "plainly mediocre".