Novoderevenkovsky District (Russian: Новодеревеньковский райо́н) is an administrative[1] and municipal[5] district (raion), one of the twenty-four in Oryol Oblast, Russia.

It is located in the northeast of the oblast.

The area of the district is 1,024.9 square kilometers (395.7 sq mi).

[2] Its administrative center is the urban locality (an urban-type settlement) of Khomutovo.

[8] The population of Khomutovo accounts for 39.5% of the district's total population.