[10] Ocean University Medical Center began as Point Pleasant Hospital in 1918 as a four-room facility in the Point Pleasant Beach home of Dr. Frank Denniston, and by the late 1920s expanded to a 16-bed building.

[15] In 2013, it began an $82 million expansion project to substantially increase the capacity of its emergency room facilities and add additional basement and third floor space, funded in part by a $5 million donation from the family of Jirair Hovnanian.

[18][19][20] In 2016, it opened its cancer center[21] and in 2017, new surgical suites,[22] as well as a "zen room" near the nurses' station where employees could break away from the work environment.

[26][27] In 2020, the hospital was rated High Performing by U.S. News & World Report for treatment of colon cancer, COPD, and heart failure.

[29] The Human Rights Campaign ranked the hospital as one of the best in the state for treating LGBTQ patients.

"[33] Ocean Medical received acknowledgment in the American Nurses Credentialing Center Magnet Recognition Program.