Octadecyltrichlorosilane

Octadecyltrichlorosilane (ODTS or n-octadecyltrichlorosilane) is an organosilicon compound with the formula CH3(CH2)17SiCl3.

A colorless liquid, it is used as a silanization agent to prepare hydrophobic stationary phase, for reversed-phase chromatography.

[2] It is also evaluated for forming self-assembled monolayers on silicon dioxide substrates.

It is flammable and hydrolyzes readily with release of hydrogen chloride.

Dodecyltrichlorosilane, an ODTS analog with shorter alkyl chain, is used for the same purpose.

NFPA 704 four-colored diamond Health 3: Short exposure could cause serious temporary or residual injury. E.g. chlorine gas Flammability 2: Must be moderately heated or exposed to relatively high ambient temperature before ignition can occur. Flash point between 38 and 93 °C (100 and 200 °F). E.g. diesel fuel Instability 2: Undergoes violent chemical change at elevated temperatures and pressures, reacts violently with water, or may form explosive mixtures with water. E.g. white phosphorus Special hazards (white): no code