The Ofanto (Italian pronunciation: [ˈɔːfanto]), known in ancient times as Aufidus or Canna,[5] is a 134 or 170 km (83 or 110 mi, depending on the sources) river in southern Italy that flows through the regions of Campania, Basilicata, and Apulia, into the Gulf of Manfredonia near Barletta.

The river's source is on the Irpinia Plateau, at 715 metres (2,346 ft) above sea level, near Nusco and Torella dei Lombardi, in the province of Avellino.

From there it runs southeast near Lioni before flowing into Lago di Conza, an artificial lake.

It then curves east for a distance and a right tributary, the Olivento, flows into it in this area.

Despite its considerable length and the extent of its basin, the average flow of water at the river mouth is fairly low, less than 15 cubic metres per second (530 cu ft/s).