[2] Offenbach Ost station was opened on 15 November 1873 on the Frankfurt-Hanau line.

Line S1 of the Rhine-Main S-Bahn has been operating on the Rodgau railway since 2003, not to Reinheim, but only as far as Rödermark-Ober-Roden station.

At the eastern end of the station, the S-Bahn line branches at a level junction towards Hanau and Offenbach-Bieber.

Line S 8 runs only during the peak hour to Hanau; at other times it begins or ends at Offenbach Ost.

Line S1 services sometimes begin in Offenbach Ost and then just runs to Frankfurt-Höchst or Hochheim.