On March 25, 2020, ʻOhana suspended service to and from Kapalua as a part of its first round of interisland schedule reductions.

[11] Beginning November 1, 2020, ʻOhana paused passenger service to Lanai and Molokai and all interisland cargo service, citing a clause in their contracts with Hawaiian pilots that stated ʻOhana flights could not be operated if interisland flights operated by Hawaiian's Boeing 717 and Airbus A321 aircraft were significantly reduced as well.

[12] Passenger service to Lanai and Molokai was eventually discontinued on January 14, 2021, effectively suspending the carrier's operations.

[13] On May 27, 2021, Hawaiian announced that it would discontinue the ʻOhana brand and service after the pandemic and resulting quarantine significantly impacted interisland travel.

[15] ʻOhana by Hawaiian served the following destinations:[16] Cargo flights were flown between Honolulu and Hilo, Kahului, Kona, and Lihue.