The highway's southern terminus is at a T-intersection with State Route 83 north of Coshocton.

Its northern terminus is at a T-intersection with the concurrency of State Route 93 north of Baltic.

In the late 1960s the highway's northern terminus was moved to its current location.

The highway leaves New Bedford and continues towards the northwest, before turning easterly.

After turning due north, the route has a T-intersection with SR 557.

[10] SR 557 has its lowest traffic counts; within the 2011 ODOT survey, the road is listed with an average annual daily traffic (AADT) of 830 vehicles on a section of highway between SR 651 and Holmes County line.