The route runs from its western terminus at SR 133 approximately 2 miles (3.2 km) north of Felicity to its eastern terminus at US 68 nearly 2 miles (3.2 km) south of Mount Orab.

Along its way, SR 774 traverses portions of eastern Clermont County and western Brown County.

No portion of this highway is included within the National Highway System, a network of routes considered to be most important for the country's economy, mobility and defense.

Originally, the highway ran from its present western terminus at State Route 133 north of Felicity to its junction with SR 125 in Hamersville.

[2][3] One year later, the highway was extended northeasterly to its present eastern terminus at US 68 south of Mount Orab.