It turns due east six miles (9.6 km) north of Lindsay, serving Payne instead.

Five miles (8 km) east of Byars, it meets U.S. Highway 177 and turns northward to join with it.

In Asher, SH-59 meets SH-39 a second time, and six miles (10 km) later it splits off from US-177 and SH-3W to head east again, through St. Louis, Oklahoma and Maud.

[5][7] A second SH-59B runs east from SH-102 through Macomb, ending at US-177 / SH-3W north of Asher, a distance of 6.93 miles (11.15 km).

(Neither Mapquest nor Google Maps show these endpoints; they instead indicate 59B runs from the vicinity of the Pottawatomie/Cleveland County line, well west of SH-102, east past that road to US-177.