It begins in the west at U.S. Route 75 Alternate in Kiefer and runs east along 151st St. South before ending at US-64 in Bixby.

Throughout much of its early years, the highway's extent was in flux, at various times serving towns such as Mounds, Drumright, Sapulpa, and Coweta.

[3] The original SH-67 began at US-75 in Mounds (US-75 at the time using the present-day route of US-75 ALT) and continuing east through far southern Tulsa County, reaching US-64 south of Bixby.

[3][6] SH-67 was re-extended to Bixby on June 7, 1943, following a more northerly route, branching off from US-75 in Kiefer, similar to the present-day one (although the final realignment of this section was not established until 1971).

On October 15, 1956, a section of gravel road beginning at the Tulsa–Wagoner County line and extending into Coweta was added to the highway system as SH-67.