The church was built as a chapel of ease in the English Georgian style, using the Roman Tuscan or Doric order, between 1745 and 1753.

In this view, the inside of the church was apparently gutted to reuse materials to rebuild homes burnt by Sherman's army.

Inside the ruins of the church lie the remains of Governor William Bull, who "greatly assisted General Oglethorpe in establishing the physical layout of Savannah, Georgia.

As of October 2015, the Old Sheldon ruins are not available to the public for hosting wedding ceremonies; however, since 1925, an annual service has been held the second Sunday after Easter by clergy from the Parish Church of St. Helena in Beaufort.

This article about a property in Beaufort County, South Carolina on the National Register of Historic Places is a stub.