It consisted of several specialized research initiatives in addition to the core table, sharing common members, brand imaging, and partner institutions.

The core table was dissolved as of September 6, 2022, transitioning to a new body called the Ontario Public Health Emergencies Science Advisory Committee (OPHESAC).

[3] On March 17, 2022, the table released a report based on data modelling that warned that Ontario would see an increase in COVID-19 cases as a result of loosening of public health restrictions.

The report indicated that protection from a third dose of a COVID-19 vaccine had plateaued for all age groups, particularly in marginalized communities, and recommended the continued wearing of masks.

[10] The Government of Ontario stated that the work conducted by the table would continue under a new mandate, with terms of reference to be announced in early September.

[13] Outgoing members of the table expressed opposition to Kieran Moore's September 1 announcement that the province would be dropping its mandatory isolation period for those testing positive for COVID-19, stating that they would have advised against the decision had they been consulted.

In addition to its core membership, the table consisted of four working groups: Behavioural Science, Congregate Care Setting, Drugs & Biologics Clinical Practice Guidelines, and Mental Health.

[22] A number of these organizations are extensions of the operations of the core OST, with near-identical brand imaging and sharing many members and partner institutions in common.

[25] The COVID-19 Rapid Evidence Access Link (REAL) is a research project based at the Dalla Lana School of Public Health.