Opuntia cespitosa, commonly called the eastern prickly pear,[1] is a species of cactus native to North America.

It is most common west of the Appalachian Mountains and east of the Mississippi River, where it is found in the Midwest, Upper South and in Ontario.

[1] Its natural habitat is in dry, open areas, such as outcrops, glades, and barrens.

It has large white spines, and a low layer of reddish-brown glochids, which break off in the skin if touched.

[2] This species was historically included in a broadly-defined Opuntia humifusa group, which is found further to the east.