Oreophrynella weiassipuensis is a species of toads in the family Bufonidae.

[4] It is possible that it is present in other localities, but most species of Oreophrynella are endemic to a single mountain.

Its characteristics are well developed post-orbital crests, well-developed webbing in hands and feet, dorsal skin that is minutely granular with scattered large tubercles particularly on the upper eyelids and flanks, and reddish brown dorsal and ventral coloration.

[2] The only known individual was found on moss in a wet forest at the bottom of a large chasm at 2,280 m (7,480 ft) above sea level.

The Brazilian part of the mountain is within the Monte Roraima National Park.