It borders Silvânia, Luziânia, Cristalina, Pires do Rio, Ipameri, Urutaí and Vianópolis.
Orizona was founded by Joaquim Fernandes de Castro and José Pereira Cardoso in 1850 when they started construction of a chapel on the banks of the Ribeirão Santa Bárbara, a tributary of the Corumbá River.
It was suggested by Dr. Raphael Leme Franco, other names proposed were Caruaba, Coema, Manhana, Orizona, Porangatu, Potira, Jubara and Oriza.
A large part of the population is still rural, relatively uncommon in the state of Goiás.
Orizona has been prospering with the production of high quality Cachaça made from sugarcane, which is exported to several countries.
Crossed by state highway GO-330 and several municipal roads, and bathed by the Corumbá and Piracanjuba rivers, the main economic activities of the area are the growing of corn, soybeans, rice sugarcane, and dairy cattle.
In addition, there are brickworks and mining companies that extract phosphates and sand.
Agricultural data 2006 In 2007 there was 1 hospital with 33 beds and 12 walk-in health clinics.