Ortica (Lombard: Ortiga [urˈtiːɡa]) is a district (quartiere) of Milan, Italy, located within the Zone 3 administrative division.

The deindustrialization that began in the 1990s significantly transformed the working-class neighborhood, which nonetheless managed to maintain its vibrant local identity.

This resilience is evident in the conversion of the former Ginori factory into a large residential complex with around 500 lofts, serving as homes, artist studios, and spaces for culinary and gastronomic endeavors.

Another major initiative started in 2015 involves the creation of 20 large murals as part of the Or.Me.

One of the latest murals, completed in 2023, is the "Mural of Rights," a tribute to 200 extraordinary individuals who have challenged social norms and made significant contributions to human and civil rights.