The Osgood River flows through the regional county municipalities of: The main neighboring watersheds of the Osgood River are: The Osgood River has its source in the heart of the hamlet of Plage-Lemieux, at Kinnear's Mills, by the confluence of the Gagné River, and the Prévost stream, a few meters from the road bridge of fourth rank.

Its confluence is located 1.6 kilometres (0.99 mi) upstream of the municipal boundary of Saint-Jacques-de-Leeds.

The toponym Osgood River evokes the name of the pioneer Osgood who had settled at the beginning of the 19th century along this river.

The spelling of this watercourse took the form of Osgoode under the pen of certain authors.

[3] The toponym Osgood River was formalized on October 6, 1983, at the Commission de toponymie du Québec.