Osmorhiza claytonii is a North American perennial herb, native to Canada and the eastern United States.

[5][6][7] Osmorhiza claytonii is a herbaceous perennial 45–90 centimetres (1–3 ft) tall and pubescent.

The seeds of this plant have barbs on the end allowing them to stick to clothing, fur, or feathers.

Small to medium-sized bees, wasps, flies, and beetles feed on the nectar and pollen of the flowers.

The caterpillars of the butterfly Papilio polyxenes (Black Swallowtail) feed on the foliage.