Otho Robards Singleton (October 14, 1814 – January 11, 1889) was a U.S. Representative from Mississippi and a member of the Confederate States Congress during the American Civil War.

[1] Lewis's father, and Otho's grandfather, was Louis Singleton, a Jessamine County sheriff and Kentucky state senator.

He graduated from St. Joseph's College, Bardstown, Kentucky, and from the law department of the University of Lexington.

Singleton was elected to the Thirty-fifth and Thirty-sixth Congresses and served from March 4, 1857, until January 12, 1861, when he withdrew.

[2] His daughter, Kate, married Junius M. Smith and lived in North Carolina.