PRO 2000 is an experimental vaginal microbicide which has been proposed as a preventive medicine for reducing the risk of contracting HIV.

Some clinical trials have shown that under some conditions it may provide some protection against HIV.

[1] Animal testing studies done on macaques have shown that PRO 2000 is effective in preventing the transmission of HIV.

Other studies have given supportive evidence that the product is safe in humans and would be an appropriate candidate for testing.

[2] A phase III clinical trial of 9385 women in sub-Saharan Africa showed that PRO 2000 was not effective in preventing transmission of HIV.