Paderno Dugnano (Milanese: Paderna Dugnan [paˈdɛrna dyˈɲãː]) is a town and comune in the Metropolitan City of Milan, in Lombardy, northern Italy.

It is bounded by comuni of Senago, Limbiate, Varedo, Cusano Milanino, Cormano, Nova Milanese, Bollate, Novate Milanese, Cinisello Balsamo.

Following the unification of Italy in 1861, a reorganization of the internal subdivisions of the country ensued.

By decree of 17 March 1869, the comuni of Paderno, Dugnano, Incirano, Cassina Amata, and Palazzolo Milanese were fused into a new comune called Paderno Milanese.

Paderno Dugnano received the honorary title of city with a presidential decree on 25 September 1989.